Initially known as RU-486, the pill was introduced in France in 1988, and anti-abortion activists fought doggedly over 12 years to keep it out of the U.S. The FDA finally gave its OK on Sept. 28, 2000, and nearly 1.4 million American women have used the pill since then.
Affording women more privacy than a surgical abortion, the pill marketed as Mifeprex now accounts for about one-quarter of U.S. abortions performed in the first nine weeks of pregnancy and about 15 percent of all U.S. abortions. In 2008, about 184,000 American women used the pill – up from 55,000 in 2001 even though the overall number of U.S. abortions wasn’t rising.
The pill’s manufacturer, Danco Laboratories, says it is effective about 95 percent of the time, with surgical procedures needed in most of the other cases to end the pregnancy or stop heavy bleeding. According to Danco, since approval in 2000 there have been eight deaths from sepsis, a bloodstream infection, among women taking the pill – a death rate of roughly 1 in 168,000 that’s far lower that the rate of women dying in childbirth.
“I just don’t see any downsides,” he said. “For those women who don’t like the invasiveness of surgery, it gives them a very important option.”
He noted the option enables a woman to undergo an abortion in the privacy of her home after getting the pill from her doctor, avoiding the need for surgery at an abortion clinic that might be targeted by protesters.
Some of the pill’s opponents “said this would make it too easy for women,” Grimes said. “That implies that the procedure should be punitive. I don’t buy that.”
The procedure, which works during the first nine weeks of pregnancy, involves swallowing Mifeprex, known chemically as mifepristone. The pill causes an embryo to detach from the uterine wall, and a second pill, misoprostol, is used two days later to cause contractions and push the embryo out of the uterus.
“While abortion is safe anyway, the earlier it’s done, the safer it is,” Saporta said.
To date, mifepristone has been approved for use in more than 35 countries, most of them affluent and industrialized. Several U.S.-based groups are part of a push to make the pill more widely available in developing countries, in hopes of reducing the number of deaths from unsafe abortions.
for the complete article … nydailynews.com/